Levels of 25 Hydroxyvitamin D in Normotensive Pregnancy and Severe Preeclampsia

Abstract

Objective: To determine the ratio of 25-hydroxyvitamin D levels in
normotensive pregnancy and severe preeclampsia.

Methods: This study was an analytic cross-sectional study with
t-test. The subject of this study consists of 17 samples normotensive
pregnancy and 17 samples severe preeclampsia. This study was
conducted and evaluated from August 2016 until December 2016 at
Department of Obstetrics and Gynecology Faculty of Medicine
Universitas Sam Ratulangi Prof. Dr. R.D. Kandou Hospital Manado
and satellite hospital in Manado. Samples were taken from serum
as much as 5 ccs and were analyzed using CLIA at Prodia clinical
laboratory. Data were analyzed with SPSS version 20.0.

Results: By using the t- test, there were significant differences in
25-hydroxyvitamin D levels between normotensive pregnancy
group (24.771  6.9567ng/ml) and severe preeclamptic group
(17.712  3.7513ng/ml), p = 0.001.

Conclusion: Levels of 25-hydroxyvitamin D in normotensive pregnancy
significantly higher compared to severe preeclampsia so it can
be concluded that the levels of 25-hydroxyvitamin D were associated
with preeclampsia.

Keywords: 25-hydroxyvitamin D, normotensive, severe preeclampsia