The Association of Creactive Protein Levels in Second Trimester of Pregnancy with Preeclampsia

  • Zulfaekasari Nasruddin Faculty of Medicine Universitas Hasanuddin/ Dr. Wahidin Sudirohusodo Hospital Makassar
  • Efendi Lukas Faculty of Medicine Universitas Hasanuddin/Dr. Wahidin Sudirohusodo Hospital Makassar
  • Umar Malinta Faculty of Medicine Universitas Hasanuddin/Dr. Wahidin Sudirohusodo Hospital Makassar
  • Maisuri T Chalid Faculty of Medicine Universitas Hasanuddin/Dr. Wahidin Sudirohusodo Hospital Makassar

Abstract

Objective: To determine C-reactive protein in second trimester
of pregnancy women who preeclamptic and non-preeclamptic
women, and to determine the relationship between the level of
C-Reactive protein of trimester two pregnancy and preeclampsia
occurrence.
Methods: This was a prospective study conducted at the policlinics
of network of academic hospitals of the Department of Obstetrics
and Gynecology of Faculty of Medicine, Universitas Hasanuddin and
policlinic of child and mother, and some Public Health Centers in
Makassar city from September 2015 - April 2016. The C-reactive
protein 115 level of pregnant women in pregnancy age of 24-28
weeks was checked, whether the subjects underwent preeclampsia
until the childbirth process. Statistics analysis used Fisher’s exact
test and Mann Whitney test.
Results: The result indicate that 9 subjects (7.8%) developed
preeclampsia and 106 subjects did not become preeclampsia. The
level of C-Reactive protein increased in preeclampsia group compared
to non preeclampsia group i.e 5.05  1.153 : 3.36  0.265,
but statistically the result is not significant (value p>0.05).
Conclusion: The average score of C-Reactive protein of preeclampsia
group is 33.5% higher than non-preeclampsia group,
even though these results cannot be used as the score to predict
the preeclampsia occurrence.
Keywords: C-reactive protein, preeclampsia, second trimester
pregnancy

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Author Biographies

Zulfaekasari Nasruddin, Faculty of Medicine Universitas Hasanuddin/ Dr. Wahidin Sudirohusodo Hospital Makassar

Department of Obstetrics and Gynecology

Efendi Lukas, Faculty of Medicine Universitas Hasanuddin/Dr. Wahidin Sudirohusodo Hospital Makassar

Department of Obstetrics and Gynecology

Umar Malinta, Faculty of Medicine Universitas Hasanuddin/Dr. Wahidin Sudirohusodo Hospital Makassar

Department of Obstetrics and Gynecology

 

Maisuri T Chalid, Faculty of Medicine Universitas Hasanuddin/Dr. Wahidin Sudirohusodo Hospital Makassar

Department of Obstetrics and Gynecology

Published
2018-01-18
Section
Research Article